johanson
Mar 8, 2003, 2:33 PM
Post #15 of 16
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Good luck Uncle Donnie. It was a pleasure putting a face that I knew to the name "Uncle Donnie" when we crossed paths at the LCS a few days ago. Hurry back with a full head of hair.
I wish more people included a picture on the posts so that I knew who I was writing to.
hey the topic is Rabies shown below is what the CDC writes about the subject
Immunization
Postexposure antirabies vaccination should always include administration of both passive antibody and vaccine, with the exception of persons who have previously received complete vaccination regimens (preexposure or postexposure) with a cell culture vaccine or persons who have been vaccinated with other types of vaccines and have had documented rabies antibody titers. These persons should receive only vaccine (see Postexposure Therapy for Previously Vaccinated Persons). The combination of RIG and vaccine is recommended for both bite and nonbite exposures (see Rationale for Treatment), regardless of the interval between exposure and initiation of treatment.
Rabies Immune Globulin Use. RIG is administered only once (i.e., at the beginning of antirabies prophylaxis) to previously unvaccinated persons to provide immediate antibodies until the patient responds to HDCV, RVA, or PCEC by actively producing antibodies. If RIG was not administered when vaccination was begun, it can be administered through the seventh day after the administration of the first dose of vaccine (78). Beyond the seventh day, RIG is not indicated since an antibody response to cell culture vaccine is presumed to have occurred. Because RIG can partially suppress active production of antibody, no more than the recommended dose should be administered (79). The recommended dose of human RIG is 20 IU/kg body weight. This formula is applicable to all age groups, including children. If anatomically feasible, the full dose of RIG should be thoroughly infiltrated in the area around and into the wounds. Any remaining volume should be injected intramuscularly at a site distant from vaccine administration. This change in the recommendations for RIG administration is based on reports of rare failures of postexposure prophylaxis when smaller amounts of RIG were infiltrated at the exposure sites (80). RIG should never be administered in the same syringe or in the same anatomical site as vaccine.
Vaccine Use. Three rabies vaccines are currently available in the United States (Table_1); any one of the three can be administered in conjunction with RIG at the beginning of postexposure therapy. A regimen of five 1-mL doses of HDCV, RVA, or PCEC should be administered intramuscularly. The first dose of the five-dose course should be administered as soon as possible after exposure. Additional doses should be administered on days 3, 7, 14, and 28 after the first vaccination. For adults, the vaccination should always be administered IM in the deltoid area. For children, the anterolateral aspect of the thigh is also acceptable. The gluteal area should never be used for HDCV, RVA, or PCEC injections because administration of HDCV in this area results in lower neutralizing antibody titers (81).
I ONLY HAVE ONE SHOT TO GO
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